Interleukin-1β Protection Against Experimental Sepsis in Mice
نویسندگان
چکیده
منابع مشابه
Protection against experimental intraabdominal sepsis by two polysaccharide immunomodulators.
Two immunomodulating polysaccharides, poly-(1-6)-beta-glucotriosyl-(1-3)-beta-glucopyranose (PGG)-glucan and Bacteroides fragilis polysaccharide A (PS A), were evaluated for the prevention of mortality and abscess formation associated with experimental intraabdominal sepsis. Prophylactic treatment with a combination of these compounds significantly reduced mortality (8% vs. 44% in the saline-tr...
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The systemic inflammatory response syndrome can be self-limited or can progress to severe sepsis and septic shock. Despite significant advances in the understanding of the molecular and cellular mechanisms of septic shock, it is still one of the most frequent and serious problems confronting clinicians in the treatments. And the effects of cannabinoid receptor 2 (CB2R) on the sepsis still remai...
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Pancreatic Secretory Trypsin Inhibitor 1 Reduces the Severity of 1 Chronic Pancreatitis in Mice Over-expressing Interleukin-1β in the 2 Pancreas 3 4 Joelle M.-J. Romac*, Rafiq A. Shahid*, Steve S. Choi, Gamze F. Karaca, Christoph B. 5 Westphalen, Timothy C. Wang, and Rodger A. Liddle 6 7 Department of Medicine, Duke University and Durham VA Medical Centers, North Carolina 8 27710. 9 Department ...
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Abscess formation is a major complication of intra-abdominal sepsis that causes significant morbidity and mortality. In such cases, Bacteroides fragilis is the predominant anaerobic isolate. In a rat model of intra-abdominal sepsis, the capsular polysaccharide complex (CPC) from B. fragilis promotes abscess formation and when administered sub-cutaneously, protects against this host response by ...
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ژورنال
عنوان ژورنال: Inflammation
سال: 2020
ISSN: 0360-3997,1573-2576
DOI: 10.1007/s10753-020-01341-7